Lyophilized standards for non-invasive prenatal testing validation

7 Aug 2026

Cold chain logistics have long been a barrier to reliable non-invasive prenatal testing (NIPT) reference materials. In this scientific poster, LGC Diagnostics & Genomics - SeraCare Clinical Diagnostics presents a new lyophilized format for their Seraseq® NIPT reference materials, stable at ambient temperature while preserving the key characteristics of circulating cell free DNA. Results across two commercial NGS-based NIPT assays confirm accurate trisomy calls, fetal sex, and fetal fraction after reconstitution.

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Resource type: Scientific poster
Page count: 1
Read time: 5 mins

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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Prenatal Testing
Lyophilized NIPT standards for reliable validation - SelectScience resources