Influence of heating rates on the thermostability characterization of antibodies by DLS and SLS

In this application note, the DynaPro^® NanoStar^® was used to study the impact of ramp rate on the apparent thermostability of trastuzumab (Her-ceptin), a commercially available mAb applied in the treatment of breast cancer. This study examined the effects of heating rate on the measured value of T_onset.