Improving the Cleanliness of DBS Extracts Using the Ostro Pass-through 96-Well Sample Preparation Plate and Single Step Method
16 Feb 2015DBS analysis can generate high analyte recoveries. However, this technique does little to eliminate endogenous interferences. Interferences, in particular residual phospholipids (PLs), are a major source of concern in bioanalysis. This application note demonstrates that the Ostro™ Pass-through 96-well Sample Preparation Plate can be used to eliminate greater 99.9% of all residual PLs.
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WatersOstro™ 96-well plate provides a novel solution for the cleanup of phospholipids in plasma and serum. Requiring minimal to no method development and using a simple protocol, this technology can be quickly implemented in order to optimize your laboratory's workflow. Removes significantly more phospholipids for cleaner extracts Improves reproducibility for more consistent, robust methods Increases throughput with easy-to-implement protocol