ResourceLife Sciences
Immunoaffinity Mass Spectrometry for Leukotriene Analysis of the Brain
18 Sept 2017Leukotrienes (LTs) are inflammatory molecules which play an important role in triggering inflammatory diseases such as asthma, neurological diseases and diabetes. As a result, it is important to better understand their role and function in terms of disease progression and their potential value as biomarkers. This application note describes the use of the Precellys® Evolution in sample preparation.
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Precellys® Evolution - Tissue Homogenizer
Bertin TechnologiesThis product has been discontinued. See the newer version of this product linked below.
Precellys® lysing kits
Bertin TechnologiesA comprehensive range of beads and tubes for sample preparation
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BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Homogenizers and BlendersHomogenizers and blenders are used to homogenize various types of material, including tissue, cells, plants, food, soil, biological and chemical samples for subsequent analysis. Lab equipment for sample homogenization includes handheld and benchtop homogenizers, bead mill, ultrasonic and multiple sample homogenizers, high shear homogenizers and blenders. Homogenizer bead and probe multipacks are available to avoid cross contamination of samples, as well as cooling systems for homogenizing temperature-sensitive samples. Homogenizers are often used in the first step of extraction of DNA, RNA and proteins from tissue and cell samples. Find the best homogenizers and blenders in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Inflammatory DiseasesNeurologyLeukotrienesBiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.