Illumina DNA Prep chemistry

19 Mar 2026

In this application note, Illumina highlights the Illumina DNA Prep, a library preparation solution that uses bead-linked transposome (BLT) chemistry to streamline next-generation sequencing workflows. Discover how BLT chemistry integrates DNA extraction, fragmentation, library preparation, and normalization into a single, rapid workflow, reducing delays and simplifying processing. Illumina also showcases the flexibility of Illumina DNA Prep for various input types and amounts, supporting applications such as whole-genome sequencing for human, microbial, and complex genomes.

Illumina DNA Prep

Illumina

A fast, integrated workflow for preparing libraries for use in a wide range of sequencing applications.

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Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
Illumina DNA Prep chemistry