ResourceLife Sciences
HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides
8 May 2013This technical note reviews data from the peer-reviewed scientific literature evaluating electrochemical response of glycoprotein-derived and related oligosaccharides to show that the changes of electrochemical response with structure are not extreme. HPAE-PAD is then compared to other common methods of oligosaccharide profiling.
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GlycobiologyGlycobiology encompasses research into the biological functions, synthesis and structures of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides. Mass spectrometers and their software are commonly used in the study of glycobiology, along with structure predicting tools, chromatography and NMR.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Glycoproteins