ResourceClinical Diagnostics
How low can fetal fraction go before your NIPT assay misses something?
12 Aug 2026Every non-invasive prenatal testing (NIPT) assay depends on sufficient fetal cell-free DNA to generate a reliable result, but does performance hold as fetal fraction declines? Discover how in partnership with Stanford University, LGC Diagnostics & Genomics – SeraCare Clinical Diagnostics used matched antepartum and postpartum cfDNA from the same donors to build a controlled fetal fraction dilution series and determined where two CE-IVD approved NIPT assays begin to lose reliability.
Resource details:
Resource type: Technical note
Page count: 6
Read time: 8 mins
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