ResourceSpectroscopy
Highly sensitive and robust LC-MS/MS solution for quantitation of nitrosamine impurities in metformin drug products
13 Jun 2021In this application note, Thermo Fisher Scientific demonstrates robust and sensitive quantitation of 10 nitrosamines with a Thermo Scientific™ TSQ Quantis™ mass spectrometer and uses the LC-SRM-MS method to quantify nitrosamine impurities in metformin drug products.
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Thermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer
Thermo Fisher ScientificEasily answer critical analytical challenges during targeted quantitation workflows in your laboratory. With its segmented quadrupoles, faster rod drivers, and improved electron multipliers, the Thermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer delivers unprecedented robustness with best-in-class sensitivity for everyday use and for every user.
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
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