Generation of mesenchymal stromal cell precursors in a 3D hollow fiber placenta co-culture model

3D hollow fiber bioreactors provide a unique cell culture environment that closely recapitulates the in vivo microenvironment. Cells are in close proximity, secreted autocrine factors are concentrated, and cells do not require splitting so that cell-to-cell interactions are enhanced and allowed to develop over time.

In this white paper, FiberCell Systems demonstrates the generation of an in vitro placenta model using a hollow fiber bioreactor. This 3D co-culture of placenta-derived cells provides a potential source of mesenchymal stromal cell precursors and can be maintained for several months of continuous collection. Download the full paper below to learn more.