From materials to microorganisms: The emergence of MALDI-TOF as a tool for clinical diagnostics
20 Feb 2024In this whitepaper, Bruker reflects on the history of MALDI-TOF, tracing its origins to Bruker's early contributions in developing the first commercial MALDI-TOF system. It examines the expanding applications of MALDI-TOF, from materials and pharmaceuticals to biomolecular analysis, driven by advancements in instrumentation, software, and mass-spectral reference libraries. The paper also discusses the ongoing evolution of MALDI Biotyper® applications, emphasizing its role in enhancing patient care through rapid, simple, and cost-effective microorganism identification in hospital settings.
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MALDI Biotyper® sirius System
Bruker Microbiology & Infection DiagnosticsThe MALDI Biotyper® employs MALDI-TOF mass spectrometry for microbial identification, facilitating unbiased identification of microorganisms within a few minutes down to the species level, starting from culture. It boasts various features, such as ease of use, rapidity, robustness, high throughput, cost-effectiveness, and efficiency, making it a must-have for microbiology laboratories.