Exploiting the potential of HoloMonitor digital holographic microscopy by combining it with 3D matrix cell culture assays
31 Aug 2022In this application note, a different type of microscope, HoloMonitor M4, based on digital holography, has demonstrated high compatibility with 3D Matrigel cell cultures. PHI researchers were able to quantify wound closure and cell movement in Matrigel by single-cell tracking. Researchers at PHI also found possibilities for further applications, such as analysis of drug response, tumor growth, metastasis, and invasion, in our 3D preparations.
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HoloMonitor® M4 Live Cell Analysis System
Phase Holographic Imaging (PHI)The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. Cell biologists worldwide use PHI’s label-free cell imager to automatically obtain accurate live-cell morphology, migration, and proliferation data as well as multi-well time-lapse videos, down to a single-cell level in real-time.