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Examples of USP Method Modernizations Using "Equivalent L/dp" and "Equivalent N" Allowed Changes with CORTECS C8 Columns

Faster methods with lower solvent consumption using CORTECS C8 and CORTECS UPLC C8 columns in USP method modernizations

19 Sept 2017

Fenoprofen is an anti-inflammatory drug used to treat pain and arthritis. The resolution standard in the USP monograph for fenoprofen separates fenoprofen and gemfibrozil. Many USP methods such as this are considered outdated due to use of old column technologies. This application note transfers USP monograph methods from fully-porous C8 columns to solid-core CORTECS C8 columns, updating and speeding up previous methods.

CORTECS® Columns

Waters

Unleash the power of your laboratory's instrumentation. CORTECS® 1.6 µm and 2.7 µm solid-core columns deliver new levels of performance. CORTECS Columns are available in both reversed-phase and HILIC options, giving you the flexibility and power to develop methods for challenging separations even faster. With different particle characteristics and innovative charged surface modifications, CORTECS Columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations. CORTECS 1.6 µm and 2.7 µm solid-core columns are suitable for use in a wide variety of applications. CORTECS Columns offer particle sizes ideal for HPLC, UHPLC, and UPLC platforms, assuring a simple, seamless method transfer with consistent results across different particle sizes and column configurations.

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Examples of USP Method Modernizations Using "Equivalent L/dp" and "Equivalent N" Allowed Changes with CORTECS C8 Columns