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Evaluating Active Ingredients in Pharmaceutical Hot Melt Extrusion Products with Raman Imaging

11 Nov 2014

Hot Melt Extrusion (HME) is a highly beneficial alternative to traditional methods for the manufacture of pharmaceutical products. In this application note, discover how Raman imaging can verify the distribution and integrity of the various components used in HME as well as identify contaminants throughout the process in order to assure a reliable and reproducible product.

Thermo Scientific DXR™xi Raman Imaging Microscope

Thermo Fisher Scientific

The Thermo Scientific™ DXR™xi Raman imaging microscope pushes Raman microscopy to the next level High performance chemical imaging is now accessible to all, accelerating research for new and experienced users alike. Optimize imaging parameters in real-time to visualize your data faster using the comprehensive Thermo Scientific™ OMNIC™xi imaging software. With its automatic feature recognition and powerful component identification, the DXRxi Raman imaging microscope will transform the way you approach materials analysis.Rapidly explore the entire sample area and find exactly what you are looking for (e.g., target particles, defects, contaminants, etc.), using our intelligent approach to chemical imaging and data collection. The Thermo Scientific™ DXR™xi Raman Imaging Microscope reveals visual information with speed and simplicity ideal for multi-user labs in academia, government, and industry. You can apply your skills and imagination to advancing scientific research, rather than learning the tools to get you there.Thermo Scientific DXR™xi Raman Imaging Microscope Features: Save time with walk-up-and-run operation regardless of user skill level Optimize imaging parameters in real-time on-screen to visualize your data faster Maximize sample throughput with intuitive workflow for demanding applications Ensure accurate measurements with - autoalignment and calibration – no tools required - automatic background compensation Adaptable configuration by any user within seconds – change the pre-aligned laser, filter and gratings without any tools Accelerate progress across your organization with expertise built into the instrument - no expertise required to set up the instrument, collect data or analyze results - anyone can generate expert results with ease - share the instrument with multiple departments, getting more done with a single instrument Applications: Nanotechnology Material science Academic research Pharmaceutical Geology

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Evaluating Active Ingredients in Pharmaceutical Hot Melt Extrusion Products with Raman Imaging