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Enhancing the Analytical Capabilities of DESI Imaging using Ion Mobility Separation

Enhancing the Analytical Capabilities of DESI Imaging using Ion Mobility Separation

28 Oct 2015

Matrix assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) coupled with ion mobility separation has demonstrated significant utility over the last decade for the separation of matrix ion species from endogenous ion species in the gas phase. Desorption electrospray ionization (DESI) has been gathering momentum as a complementary MSI technique to the more traditional SIMS and MALDI-MS approached. This poster compares and contrasts DESI imaging with MALDI imaging on the same ion mobility enabled mass spectrometer.

MALDI SYNAPT G2-Si High Definition Mass Spectrometry

Waters

Redefining Resolution - Resolution in 3 Dimensions. MALDI SYNAPT G2-Si is a uniquely powerful and versatile MS platform. It's the only way to combine multiple dimensions of separation for analysis of complex samples, from imaging to biological research to chemical materials characterization. The MALDI SYNAPT G2-Si gives you high performance, accurate mass MALDI MS/MS, superior post-ionization separation with T-Wave IMS, High Definition Imaging (HDI) MALDI workflows, versatile experimental options, and the ultimate UPLC/MS/MS performance.

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Enhancing the Analytical Capabilities of DESI Imaging using Ion Mobility Separation