ResourceClinical Diagnostics
Enhancing cfDNA NGS with Agilent Avida DNA Workflow & Seraseq Mutation Mix v4
18 Aug 2026Explore the Agilent Avida DNA workflow and Seraseq® cfDNA Mutation Mix v4 for improving low-frequency mutation detection in cfDNA. Discover how hybridization enrichment and methods on Illumina platforms enhance sensitivity at 0.2% variant allele frequency (VAF) for more accurate mutation assays.
Resource details:
Resource type: Application note
Page count: 7
Read time: 10 mins
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Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.cfDNA