ResourceLife Sciences
Enhanced plasmid production – Achieving a 21-fold increase in plasmids
9 Oct 2024The demand for plasmid DNA (pDNA) has increased over the last few years as a result of the high demand for gene therapies and DNA vaccinations. Therefore, an increased production of pDNA with a cost-effective, reproducible, and reliable purification and quality control system is required. Explore how the combination of the Ultra Yield® flasks with the enriched Plasmid+® medium and the AirOtop® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.
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DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.PlasmidPlasmid DNA