Endotoxin Removal from Water Buffer, Neutral Sugars, and Certain Biological Solutions

Endotoxin Removal from Water Buffer, Neutral Sugars, and Certain Biological Solutions

5 Feb 2016

This application note from Pall Laboratories describes the removal of endotoxins using the Acrodisc® unit with positively-charged, hydrophilic Mustang® E membrane, which can be used on different solutions. Endotoxin is a complex aggregate of acidic lipopolysaccharides (LPS) and can cause false readings in cell-based assays.

Acrodisc® WBC Syringe Filter

Pall Life Sciences - Laboratory, Food, Beverage

Pall Life Sciences' Acrodisc WBC premium syringe filter is an innovative filtration device designed specifically for use in the capture and recovery of Leukocytes and the separation of red blood cells. The Acrodisc WBC filter contains Pall's patented Leukosorb media. Leukosorb is a fibrous matrix that uses a multimodal approach of size exclusion and adsorption to capture and recover leukocytes from whole blood samples while allowing Red Blood Cells (RBCs) and platelets to flow through the membrane. With the Acrodisc WBC, the uniquely designed filter does all the difficult capture work, resulting in more efficient white blood cell separation as compared to Buffy Coat density gradient methods. The Acrodisc WBC yields greater cell capture and recovery with less sample compared to larger filter formats and also exudes very low hold up volume as compared to larger white blood cell isolation filters (hold up volume   Applications: Antigenic specificity Antigen modulation studies Cell receptor analysis Lymphocyte recovery for cell therapy Stem cell research applications  

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Acrodisc® PSF 0.2 µm Syringe Filters

Pall Life Sciences - Laboratory, Food, Beverage

Acrodisc PSF syringe filters are available in many membrane types, sizes, and packaging configurations to fit all applications. These are the only syringe filters to receive Caliper Life Sciences Automation Certified guarantee, providing: Smooth operation and worry-free performance in automated applications with smooth filter-to-filter release, consistent turret advancement, exceptional housing strength, and strict outside filter geometry. Best protection for HPLC columns – extend column life as much as 46 times. Maximum throughput with the GxF multi-layer prefilter.

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