ResourceDrug Discovery & Development
Eliminating hemostatic risk in plasma-derived biotherapeutic formulations
14 May 2026Plasma‑derived biotherapeutics face a persistent challenge: traditional ethanol‑based fractionation can introduce procoagulant contaminants such as FXIa and kallikrein activators, creating hemostatic risk and limiting both yield and safety. As global demand for IgG continues to outpace supply, safer, faster, and more stable manufacturing approaches are urgently needed.
Explore this resource to see how next‑generation ion‑exchange‑based purification technologies and integrated analytical workflows can remove trace clotting factors, enhance IgG recovery, and support the development of cleaner, more reliable plasma‑derived therapeutics.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
PlasmaBiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in in vivo diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.