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Elevate your mAb aggregate analysis with the Agilent 1290 Infinity II Bio LC System

27 Jun 2021

Modern columns for size exclusion chromatography (SEC) separation of proteins comprise material with sub-2 μm particles for optimum resolution. This application note demonstrates the superior resolution in SEC protein separation made possible by the Agilent 1290 Infinity II Bio LC System.

Agilent 1290 Infinity II Bio LC System

Agilent Technologies

The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Protein SeparationChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.
Elevate your mAb aggregate analysis with the Agilent 1290 Infinity II Bio LC System