Drug toxicity profiling with the Spark Cyto and D300e Digital Dispenser

14 Jul 2022

Analyzing the dose-response relationship using cell-based assays is essential to understanding a drug’s efficacy. In this application note, Tecan uses the D300e and Spark Cyto to comprehensively capture an anti-cancer drug’s efficacy profile, tracking cell viability with nine doses at 25 time points using luminescence-based and bright field imaging technologies simultaneously.

D300e Digital Dispenser

Tecan

The D300e Digital Dispenser* uses direct digital dispensing technology to enable rapid delivery of picoliter to microliter sample volumes. It delivers fast, reliable performance across a large dynamic range, eliminating the need for slow, error-prone and wasteful serial dilutions for creation of dose-response curves and enabling miniaturized qPCR reaction set-up.

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