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Don’t Overestimate Cannabidiol During Medical Cannabis Potency Testing by Gas Chromatography

2 Nov 2017

Accurate potency testing of medical cannabis with gas chromatography (GC) depends principally on choosing a column with the right selectivity; otherwise, coelutions between cannabinoids of interest may cause error in potency measurements. Potency testing for medical marijuana is often done using “5-type” GC columns. However, on 5-type columns cannabidiol can coelute with cannabichromene. This application note demonstrates that to identify and report both of these compounds accurately, a GC column with a different stationary phase is needed.

Rxi®-17 (Fused Silica) GC columns

Restek Corp.

Restek's former Rtx®-17 columns are now manufactured using new Rxi® column technology--for unsurpassed inertness, ultra-low bleed, guaranteed reproducibility, and unmatched performance!

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.CannabinoidsCannabinoids are compounds found in cannabis that have therapeutic effects, such as pain relief, anti-inflammatory properties, and potential neuroprotective benefits. Research into cannabinoids is growing, particularly in the fields of pain management, neurological diseases, and cancer treatments. Browse our peer-reviewed product directory to find the best cannabinoid research tools, compare products, check reviews, and get pricing directly from manufacturers.Cannabis