ResourceSpectroscopy
Detection and Quantification of Formaldehyde by Derivatization with Pentafluorobenzylhydroxyl Amine in Pharmaceutical Excipients
12 Jul 2012This application note presents a simple and effective method for the determination of formaldehyde in pharmaceutical excipients using SHS-GC/MS. This is a fast and reliable method that can be used for the quantification of low-molecular-weight aldehydes in most excipients commonly used in pharmaceutical products. Excellent quantification and linear instrument response was reported across a 1 to 50 ppb concentration range of formaldehyde.
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GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.FormaldehydeAmines
