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Detection and Confirmation of the Metabolites of a Novel Candidate Cancer Therapeutic using the Automated Collection of Simultaneous MRM and Full Scan LC/MS/MS

25 Oct 2011

This poster presents the use of a new software tool and high sensitivity fast scanning tandem quadrupole MS for the automated generation of MRM triggered full scan MS/MS experiments to simultaneously detect, quantify and confirm drug related metabolites in in-vivo studies.

Xevo TQ-S

Waters

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated method development for sensitive and robust methods. Reducing complexity, increasing ease of use, and ensuring the correct result every time.

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Detection and Confirmation of the Metabolites of a Novel Candidate Cancer Therapeutic using the Automated Collection of Simultaneous MRM and Full Scan LC/MS/MS