Culture and Assay Systems Used for 3D Cell Culture

Culture and Assay Systems Used for 3D Cell Culture

2 May 2017

This application note will review the general principles, advantages and current limits of in vitro 3D cell culture systems, covering cell biology, tissue modelling and drug discovery and toxicity. The most commonly used matrices for in vitro 3D culture such as ECM-based hydrogels and their applications will also be covered. 3D cell culture methods have been developed over the years to address the limitations of 2D cultures, particularly their physiological irrelevance and inability to emulate in vivo conditions.

10-Layer CellCube® Module with 8,500cm² Growth Surface

Corning Life Sciences

The CellCube Module is an integral, encapsulated, sterile, single-use device that is 100% pressure-hold tested before shipment. It is comprised of a series of parallel, styrene plates joined to create thin, sealed, laminar flow spaces between adjacent plates. Each culture plate receives proprietary tissue culture treatment prior to assembly to ensure dense, uniform cell growth.These CellCube Modules provide:a series of parallel, polystyrene plates joined to create thin, sealed, laminar flow spaces between adjacent plates.8,500cm2 polystyrene growth surface optimally treated for the growth of attachment dependent cells.a perfused environment which more closely simulates in vivo conditions and reliably distributes nutrients and oxygen.an integral, encapsulated, sterile, single-use device that is 100% pressure-hold tested before shipment

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Culture and Assay Systems Used for 3D Cell Culture