Comparison of Single Use Bioreactor BIOSTAT® CultiBag RM and Reusable STR for Cultivation of CHO Cells in Serum Free Media

BIOSTAT® CultiBag RM single-use bioreactor for the cultivation of all cell types, including mammalian cells, plant cells, insect cells, stem cells and microbial cells. Application-driven packages are available for culturing from 100 ml to 300 l. BIOSTAT® CultiBag RM is a single-use bioreactor utilising rocking motion agitation with low shear. The feedback control loops using single use sensors for pH and DO, bring new levels of confidence to process development.

Innovative Bioreactor, Sensor and Stirrer Technology The BIOSTAT® CultiBag STR Plus is a stirred single use bioreactor available from small scale to large scale cultivation up to 1000L. Its design is entirely based on the conventional gold standards coming from the stainless steel systems, allowing for easy scale-up and transfer from stainless steel solutions. The BIOSTAT® CultiBag STR Plus consists of one BIOSTAT® STR Plus Control Tower, one bag holder, a single-use CultiBag STR and superior BioPAT® MFCS/DA data logging software. Single as well as twin versions are available.It is ideal for: Cell Culture applications Industrial and academic research Process development Process optimization Pilot scale production Seed cultivation for large scale bioreactors Production scale Features: Completely single use bioreactor in traditional design Top driven stirrer with magnetic coupling Application driven fully flexible gassing system Available as single and twin version User-friendly touch screen interface for easy operation Single use optical DO & pH sensors for measurement Single use bags available with working volumes of 50L, 200L, 500L and 1000L Validation & Extractible guide available