Comparison of ionization types and precursor ions for quantitative analysis of 25-hydroxyvitamin D on a TSQ Altis MD mass spectrometer
10 Nov 2023In this application note, Thermo Fisher Scientific compares variations of an analytical method for detecting and quantifying 25-hydroxyvitamin D2 and D3 using a Thermo Scientific™ TSQ Altis™ MD mass spectrometer. The note emphasizes the essential role of vitamin D in various biological functions, including promoting the absorption of calcium and supporting healthy bone growth. It highlights that vitamin D deficiency can lead to weakened bones, with manifestations like rickets in children and osteomalacia in adults, causing soft and malformed bones, reduced growth, and muscle weakness.
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TSQ Altis™ MD Mass Spectrometer
Thermo Fisher ScientificDevelop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories.