Comparison of Biosimilar and Innovator Monoclonal Antibody Rituximab

25 Jan 2018

This study investigated the monoclonal antibody rituximab and its use in biotherapeutics. The physicochemical and biological characterization of a biosimilar rituximab was carried out using an Agilent 1260 Bio-inert LC system, Bio-columns, and Agilent OpenLAB CDS Match Compare Software tool.

Agilent 1260 Infinity II Bio-Inert LC System

Agilent Technologies

The 1260 Infinity II Bio-Inert LC is a dedicated solution for analysis of large biomolecules in biological samples, including monoclonal antibody (mAb) and protein analysis. Metal-free components in the sample flow path and the absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.

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OpenLAB CDS ChemStation Edition

Agilent Technologies

Offers the most complete instrument control of Agilent LC, GC, CE, CE/MS, and LC/MS instruments systems you have now, with limited instrument control of other vendors’ systems. Plus, take full advantage of the advanced features of the Agilent GC and LC instruments you have now and new instruments, when released.

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Comparison of Biosimilar and Innovator Monoclonal Antibody Rituximab