Comparative tumor model study: Melanoma cancer WM4071-2 PDX cells

11 Oct 2024

The B-NDG model is a single knockout mouse with an ultra immunodeficient phenotype. WM4071-2 patient-derived xenograft cells from The Wistar Institute (Philadelphia, PA) were implanted into cohorts of B-NDG, NSG™ and athymic nude mice. Explore how tumors grew faster and more consistently in the B-NDG model, which resulted in time and money savings.

Links

Tags

Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. Tumor GrowthCancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
Comparative tumor model study: Melanoma Cancer WM4071-2 PDX cells