Calcium Flux Assay for In Vitro Neurotoxicity Studies and Drug Screening

12 Feb 2019

Neurons are electrically excitable cells in the central and peripheral nervous system that process and transmit information through electrical and chemical signals. These signals occur via synapses that allow neurons connecting to each other to form neuronal networks.

EarlyTox Cardiotoxicity Kit

Molecular Devices®

The EarlyTox™ Cardiotoxicity Kit provides a fast, simple, and reliable fluorescence-based method for identifying cardiotoxic compounds in a biorelevant assay using stem-cell derived cardiomyocytes. Leveraging our proprietary masking technology with our novel calcium sensitive indicator, researchers can:• Eliminate cardiotoxic compounds and identify potential drug candidates• Measure 384 samples in minutes rather than hours• Minimize non-specific effect of dye on beat characteristics• Reduce well-to-well variation and improve data quality• Largest signal dynamic range available• Benchmark against three reference compounds: isoproterenol, sotalol and propranolol

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SoftMax® Pro Microplate Data Acquisition & Analysis Software

Molecular Devices®

SoftMax ® Pro Software is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options. Every step has been optimized for data acquired from a Molecular Devices microplate reader or data imported from another source to simplify analysis and reporting. FDA 21 CFR Part 11 compliance tools are available for regulated laboratories providing end-to-end chain of custody.

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