Bulk Production of Cell Aggregates in Microcavity Vessels and Dispensing to Corning® Microplates for High-Throughput Screening

9 May 2018

Three-dimensional cell culture is increasing in pharmaceutical and biotechnology research. The Corning Microcavity vessel platform was developed as a tool for scientists working with 3D cell aggregate models in order to easily scale up their 3D culture production. This poster demonstrates the production of 3D cell aggregrates in bulk format using the Microcavity platform, followed by sorting and dispensing.

Corning® 384-well Black/Clear Round Bottom Ultra-Low Attachment Spheroid Microplate, Bulk Packed 10 per Bag, with Lid, Sterile

Corning Life Sciences

Ultra-Low Attachment microplates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation and cellular activation Surface is noncytotoxic, biologically inert and nondegradable Sterilized by gamma irradiation Black wall microplates have low background fluorescence, minimal light scatter and reduced crosstalk Opaque walls to prevent well-to-well crosstalk Can be used for both top and bottom reading instruments Bulk packed 10 per bag Novel well geometry aids formation of spheroids in center of well Optically clear round bottom with black opaque microplate body

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Bulk Production of Cell Aggregates in Microcavity Vessels and Dispensing to Corning® Microplates for High-Throughput Screening