Automated Ion Chromatographic Determinations Over Six Orders of Magnitude

This application note discusses trace analysis methods with contamination-free sample handling and accurate calibration graphs. The method calibration in the low ppb and ppt range is critical, as standard solutions in this range are difficult to handle without introducing errors. Moreover, if the sample concentration is outside the calibration range, laborious and error-prone dilution or preconcentration is required. These drawbacks are overcome by inline coupling of the patented 800 Dosino and Metrohm`s intelligent ion chromatographs (ICs). The Dosino enables high-precision dosing of variable solution volumes into the sample loop or preconcentration column of the IC.