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Analyzing the Effect of Pipette Tip Geometries on Fluid Velocity and Shear Strain Rate

Beckman Coulter Diagnostics

Biomek wide bore vs. standard pipette tip

9 May 2018

Sample preparation protocols specify the need for “wide bore” pipette tips and cannulas to minimize the inadvertent harm, which can be applied to native biological sample matrices during sample preparation. Loss of biological sample integrity can occur due to the pipette tips’ small internal orifice diameter and the speed of aspiration and dispense during pipetting. Biomek Wide Bore Pipette Tips have been designed to address such sample preparation challenges. Through the use of Computational Fluid Dynamics (CFD) software, physical forces and flow characteristics within a pipette tip during pipetting have been simulated. Comparisons of pipette tip orifice diameters can be analyzed for such parameters as fluid (sample) velocity, wall shear, and shear strain rate.

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Biomek® 4000 Laboratory Automation Workstation

Beckman Coulter Life Sciences

Biomek Liquid Handlers enable you can spend less time on manual process and more time on powerful discoveries. Beckman Coulter Life Sciences is a leader when it comes to providing solutions and support that cover the full spectrum of the NGS sample preparation workflow with reagents and automation. Throughput options allow you to choose the right solution for your laboratory.

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Analyzing the Effect of Pipette Tip Geometries on Fluid Velocity and Shear Strain Rate