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Analysis of sucrose proposed in USP-NF Pharmacopeial Forum (SC1011-7F)

3 Mar 2023

According to the United States Pharmacopeia and the National Formulary Pharmacopeial Forum, sucrose assay and analysis of impurities (related substances) should be carried out with a HPLC method and a column filled with L19 packing material, and meet certain requirements. In this application note, Showa Denko shows that the use of a sugar analysis column, EP SC1011-7F, which confirmed the requirements were met.

SUGAR SC1011

Showa Denko Europe GmbH

Sugar series columns using dual mode of Ligand Exchange and Size Exclusion Chromatography for specific separation of sugars. Separates mono and di-saccharides by combination of ligand exchange and size exclusion mode Counter ion: Ca2+ (divalent metal ions attached to the packing material separate saccharides from sugar alcohol as these columns retain sugar alcohol strongly.) Only water is required for the analysis (cost and eco-friendly)

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Analysis of sucrose proposed in USP-NF Pharmacopeial Forum (SC1011-7F)