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Analysis of Pharmaceuticals and Pesticides in Bottled, Tap, and Surface Water Using ACQUITY UPLC Systems with 2D-LC Technology

12 Nov 2014

This application demonstrated the disruptive nature of ACQUITY UPLC Systems with 2D-LC Technology with a Xevo TQD Mass Spectrometer. The application targeted the analysis of PPCP’s and pesticides in bottled, tap, and surface water. The limit of detection in this study was 1.0 ppt with a 10:1 enrichment from the extraction protocol (15 min total) and a 200:1 enrichment from the at-column dilution option, for a total of 2000:1. The recovery data for bottled, tap, and surface water samples using a micro extraction protocol shows comparable results to application with macro extraction protocols.

ACQUITY Systems with 2D Technology

Waters

UPLC Technology Extends To Two Dimensions For chromatographers who require additional capabilities to increase their speed of analysis, gain sensitivity and selectivity, and perform orthogonal separations, ACQUITY UPLC® Systems can meet these needs by controlling multiple valves and pumps for 2D separations. The resolution, sensitivity, and throughput benefits of UPLC® Technology are even more important in 2D applications. Waters’ 2D Technology solutions for the ACQUITY UPLC, ACQUITY UPLC H-Class, and ACQUITY UPLC H-Class Bio systems are purpose-built, from plumbing to software to valve control, to provide reproducible and consistent results for specific applications. Features:   •  Ready-to-use configurations to get you to successful 2D UPLC experiments faster, with less troubleshooting and more confidence   •  ACQUITY UPLC systems and proven columns enable best-in-class selectivity and sensitivity

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Analysis of Pharmaceuticals and Pesticides in Bottled, Tap, and Surface Water Using ACQUITY UPLC Systems with 2D-LC Technology