ResourceSpectroscopy

Advantages of Size/Shape Ion Mobility Separation for Metabolite ID: Collecting Cleaner and More Specific Data than Using HRMS Alone

24 Feb 2015

Metabolite identification requires confident assignment of drug-related components. This application note demonstrates the ability of the UNIFI® Collision Cross Section (CCS) Research Edition to process ion mobility (HDMS™) data in a routine, workflow-driven manner. It also shows the utility of ion mobility to allow complex samples to be understood without complication from unrelated interferences.

SYNAPT G2-Si HDMS

Waters

The Waters SYNAPT G2-Si High Definition Mass Spectrometry provides complete characterization of complex mixtures and molecules with unique levels of MS performance, industry leading informatics and unparalleled platform versatility.Through high-efficiency T-Wave™ ion mobility you can get superior separation, enhance the peak capacity, specificity and sensitivity of your analysis and transform your targeted and untargeted workflows. Ultimate UPLC/MS/MS performance, data independent and data dependant T-Wave IMS solution, CID and ETD fragmentation capabilities and a wide range of experimental options. This system gives you additional dimension of separation, based on molecular size and shape. It delivers a third dimension to your analysis, proven to transform your analytical perspective whatever the application.

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Advantages of Size/Shape Ion Mobility Separation for Metabolite ID: Collecting Cleaner and More Specific Data than Using HRMS Alone