Accurate, IVDR compliant NGS variant calling using the Illumina DRAGEN Server for NextSeq 550Dx Instruments

In this application note, Illumina highlights how the DRAGEN™ Server for NextSeq™ 550Dx enables fast and highly accurate variant calling for diagnostic next-generation sequencing workflows. Illumina describes a complete DNA-to-data solution combining Illumina DNA Prep with Enrichment Dx library preparation, sequencing on the NextSeq 550Dx Instrument, and secondary analysis with DRAGEN software, and demonstrates how this workflow supports flexible, easy-to-use targeted enrichment for in vitro diagnostic applications.