Accelerating 3D Microtissue Production
13 Sept 2015Preclinical drug development relies on advanced in vitro models with a high degree of standardization to achieve maximal predictivity for an efficient compound de-risking strategy. InSphero's scaffold-free organo-typic three-dimensional (3D) microtissue spheroids fulfil these requirements as they can be produced and assayed by standard automated liquid handling systems. The Integra Viaflo 96 Channel Electronic Hand-Held Pipette is perfectly suited to produce 3D microtissues in InSphero's GravityPLUSTM hanging drop plate and to further culture and process them in the GravityTRAPTM platform, as described in this application note.
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VIAFLO 96 – Electronic 24 and 96 Channel Handheld Pipette
INTEGRA BiosciencesVIAFLO 96 increases productivity of sample preparation in microplates. It is used like a standard handheld pipette. It is hand-controlled but movements are supported by motors for an effortless workflow and precise targeting of the microplate wells. The working volume range of VIAFLO 96 can be quickly adapted to the application’s requirements by changing the pipetting heads. The 24 channel heads are available in the volume ranges 10-300 µl and 50-1250 µl and the 96 channel heads in the volume ranges 0.5-12.5 µl, 2-50µl, 5–125 µl, 10–300 µl and 50–1250 µl. VIAFLO 96 benefits from the innovative GripTip system. The special pipette tips, together with the unique tip fitting, form an integral system. It guarantees tips will not fall off during pipetting and provides a reliable sealing of every tip. VIAFLO 96 can be used for sample transfers from reservoir to plate, plate to plate or within plates. Features and Benefits: • VIAFLO 96 is used like a handheld pipette and has an intuitive user interface, freeing staff from training time. • Pipetting heads can be changed for an optimal instrument adaption to different volume ranges, increasing accuracy and precision. • The innovative GripTip system provides a reliable sealing of every tip and guarantees that tips will never fall off, providing safe and reproducible assay preparation. • Various pipetting modes are available for increased productivity and application customization.