A Simplified, Integrated Solution for Untargeted Metabolomics

7 Jun 2017

Metabolomics focuses on the chemical processes central to cellular metabolism, giving scientists a snapshot of the cellular metabolic state, or metabolome at a given time. However, they can be increasingly challenging workflows to setup for the novice metabolomics researcher or the technician. Therefore, a robust solution for screening metabolomics samples is of increased interest and the need for a more integrated and routine mass spectrometry system is in demand. The new X500R QTOF System was developed for routine, robust workflows and requires minimal MS expertise. The system integrates all data acquisition; processing and review as well as reporting into a single piece of easy to use, easy to learn software.

MarkerView software

SCIEX

MarkerView software does the heavy lifting for you to rigorously mine data and provide statistical analysis and visualization of large numbers of samples. MarkerView software is ideal for profiling and comparing the composition within your samples in order to gain valuable insight into any trends within your mass spectral. This post-acquisition analysis software reduces the need for manual intervention empowering you to explore statistical correlations with direct connections back to the raw data from your SCIEX mass spectrometer, so you can confidently and effectively solve even your most complex analysis.  

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X500R QTOF system

SCIEX

Made just for you, the X500R QTOF system is the first robust, high-performance high resolution MS system designed for routine use. The simple, balanced hardware design combined with the SCIEX OS software user interface makes the system easy to learn, and the robust performance ensures you get the right results quickly, reliably, and with maximum uptime for all your routine testing applications.   Features: Simplicity in hardware and software design for ease of operation, regardless of technician's skill set. Robustness delivered for analysis of complex samples with the Turbo V ionization source. Balanced across key criteria to deliver performance without compromise. Superior instrument uptime with fast and efficient maintenance. Stability through long runs with automated calibration. The sleek, compact design requires little lab space.

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BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.Protein BiologyBiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.