ResourceLife Sciences
A Novel NanoLuc Profurimazine-Based Real-Time Bioluminescent Cell Viability Assay
8 Sept 2014This poster describes a new real-time cell viability assay, RealTime-Glo Metabolic Cell Viability Assay, which utilizes NanoLuc® luciferase and a novel profurimazine substrate to determine the number of viable cells in culture through measurement of the reducing capacity of the cell.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell ViabilityCell viability assays assess the health of cells and their ability to proliferate. These tests are crucial in drug development, toxicity testing, and cell-based research. Common methods for assessing viability include MTT, live/dead assays, and flow cytometry. Browse our peer-reviewed product directory to find the best tools for cell viability assays, compare products, check reviews, and get pricing directly from manufacturers.LuciferaseAssay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.