A high content anti-cancer drug screening using automated cell cycle assay by the CELENA X High Content Imaging System

28 May 2026

This application note demonstrates how the CELENA® X High Content Imaging System can be used to perform automated cell cycle assays for anti-cancer drug screening. Using fluorescence imaging and analysis pipelines, the system enables evaluation of dose-dependent effects of compounds such as paclitaxel and thymidine on cell cycle progression. The workflow supports high-throughput, quantitative analysis of drug responses, helping accelerate early-stage drug discovery.

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Fluorescence ImagingHigh Content ImagingHigh content imaging is a method combining two or more fluorescent microscopy experiments to identify substances that alter a cell’s phenotype in a desired manner. The process is adapted to multi-well plates and both the image acquisition and analysis are automated.Cell Cycle AnalysisHigh Throughput ScreeningOncologyThe branch of medical science that deals with the diagnosis and treatment of cancer is known as oncology.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.