UHPLC and HPLC Products & Reviews

Novel pH 1-12 stable C18 that delivers robust methods and improved peak shape for bases.

This unique C18 phase yields increased hydrogen bonding with hydrophobic selectivity, resulting in improved peak shape for basic compounds and increased retention of acidic compounds.

Balanced C18 phase that provides the highest degree of hydrophobic selectivity relative to the other Kinetex phases.

Used under HILIC running conditions, this phase provides the highest polar selectivity for retention and separation of hydrophilic compounds.

Polymer-based columns for aqueous Size Exclusion Chromatography (GFC) suitable for light scattering detector.

Polymer-based columns for aqueous Size Exclusion Chromatography (GFC).

Polymer-based columns for Hydrophilic Interaction Chromatography.

Polymer-based columns for Ligand Exchange Chromatography.

Sugar series columns using dual mode of Ligand Exchange and Size Exclusion Chromatography for specific separation of sugars. Separates mono and di-saccharides by combination of ligand exchange and size exclusion mode Counter ion: Ca2+ (divalent metal ions attached to the packing material separate saccharides from sugar alcohol as these columns retain sugar alcohol strongly.) Only water is required for the analysis (c…

The next generation in UHPLC Fittings.

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Achieve excellent linearity and noise performance to support a wide operating range and trace detection using the Thermo Scientific™ Vanquish™ Variable Wavelength Detector F. This detector is integrated in the Vanquish UHPLC system when you need more versatility, and robust and high-performance UV-Vis absorption detection to measure your sample. With up to 250 Hz, the detector keeps pace with any current and future UHPLC detec…

Get maximum fluorescence detection effectiveness from the sophisticated design of multiple measurement features in the Thermo Scientific™ Vanquish™ Fluorescence Detector. Monitor up to four excitation/emission wavelength pairs simultaneously in multichannel operation mode with ultrafast wavelength switching, or scan your chromatogram for the best emission/excitation wavelengths with fluorescence fields. The optical design prov…

The Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, robustness and reliability.

Improve your productivity and sample knowledge for a faster return on investment with the Thermo Scientific™ Vanquish™ Duo UHPLC systems. Vanquish Duo UHPLC systems use a separate second flow path in one integrated system. With the Thermo Scientific™ Vanquish™ Duo UHPLC system for Dual LC, double your throughput or deepen your sample knowledge. Run the same method on both flow paths or two different methods simultaneously on o…

Speed up Bio-UHPLC workflows without redeveloping existing methods. The Thermo Scientific™ UltiMate™ 3000 BioRS Dual System offers outstanding LC and advanced bio-UHPLC capabilities. Two independently operating gradient pumps and smart column switching save time. Offline fractionation combines noncompatible chemistries in one workflow. With our unique fractionation autosampler, the system can completely automate multiple UHPLC…

Enjoy cost effective access to UHPLC separations in a simple, expandable system where modularity makes anything possible. The Thermo Scientific™ UltiMate™ 3000 Basic Manual system offers unique LC and entry level UHPLC capabilities without compromising on quality and robustness. The basic manual system is perfect for teaching or low sample throughput, routine applications. As an LC/UHPLC “starter kit”, this modular system can…

For flexibility across a broad range of analytical LC applications with the highest degree of choice in solvent proportioning and mixing, the Thermo Scientific™ UltiMate™ LPG-3400SD Standard Quaternary Pump is the pump of choice. Up to four solvents may be used for convenient method development, system flushing or solvent preparation. With support for pressures up to 62 MPa (9,000 psi/620 bar) at flow rates of up to 10mL/min.,…

Inertsil ODS columns are general-purpose reversed phase C18 columns, available in 5-µm and 10-µm particle sizes. It was the first of the ODS columns from GL Sciences, introduced back in 1986. We currently recommend InertSustain C18 or Inertsil ODS-4 columns for all new method developments.

2mL Clear Glass Vial with Marking Patch and 350uL Conical Pulled-Point Clear Glass Insert Approved for LC/GC Class 10,000 Clean Room Packed Vials and Inserts

Polymer-based column for aqueous Size Exclusion Chromatography (GFC) suitable for light scattering detector.

For HPLC, Spectrophotometry and Applications requiring ACS grade solvent

500 g, cation exchange resin, sodium form, 1% crosslinkage, 50–100 dry mesh size, 300–1,180 µm wet bead size, ~3,500 MW limit

An ODS column with Anion and Cation Exchange. Weak ionic ligands adequately bonded to this material optimized for the separation of basic/acidic compounds at neutral pH.

In HPLC analysis, especially in gradient elution, some unexpected peaks, which are usually called Ghost peaks, may appear in a chromatogram. Ghost peaks my appear for many reasons, including residual in injection valve, water pollution impurities and unknown components in sample. Generally, they are caused by impurities from mobile phase. Welch Ghost-Buster Column can solve this problem easily! Welch Ghost-Buster colu…