Electrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.
XenoWorks, a modular system designed to meet a wide variety of microinjection application needs. Our experience with precision motor control has culminated in this state of the art system. Features:XenoWorks Micromanipulator: Exceptionally smooth and responsive micropipette movement Six movement sensitivities Height- and tension-adjustable inverted joystick for optimal ergonomics Up to 25mm of movement in three axes…
Designed primarily for transgenic mammal workstations, the XenoWorks Digital Microinjector is capable of holding oocytes and early embryos immobile while simultaneously providing a separate pressure channel for pronuclear microinjection of DNA or the gentle control of embryonic stem cells as they are transferred into blastocysts. Features of the XenoWorks Digital Microinjector:• Built-in compressor with remote user interface •…
The Manual Injector is a manual syringe driver for pneumatic or hydraulic control of injection needles or holding pipettes. It is suitable for injecting volumes in the nanoliter to microliter range. It is also widely used as a fluid control device for applications requiring sensitive manual control of the displacement of microneedle contents. The system is constructed from the highest quality parts. The base assembly is black…
Sutter Instrument Company, in addition to the finest micropipette pullers available, offers a wide selection of high quality capillary glasses in various sizes and materials. Though there are many types and sizes of capillary glass available, we have carefully selected only those that pass our criteria. Our expertise in micropipette technology assures you of precision and high quality. Types of glass available: Borosilica…
The Movable Objective Microscope (MOM) is designed to be an ultra-stable, versatile, fluorescence platform for electrophysiology experiments. The MOM is a new alternative to the popular technique employing a fixed-stage, upright microscope on a translating X-Y table. The advantage of the MOM is that only the microscope objective is moving in 3 dimensions. The main frame of the microscope, including the light source and camera…
Triple EmissionThe TripleSplit 3-way image splitter from Cairn Research is a simple device for dividing an image into either one, two or three separate, spatially equivalent components which can be displayed side by side on a single camera chip. Download data sheet Splitting is usually performed on the basis of wavelength or polarisation, allowing applications where there is a requirement for simultaneous, or high speed, acqui…
Our New LED Based Flash Photolysis SystemThe Cairn Optoflash is the latest member of the Cairn OptoLED family. It uses our established LED head and microscope coupling designs, but is optimised for short-term intense illumination. This makes it particularly suitable for the photoactivation of “caged” neurotransmitter or other compounds, and for the important emerging application of channel rhodopsin activation. The maximum cur…
Ultra Stable and Instantaneous Wavelength Switching Recent developments in Light Emitting Diode [LED] technology have yielded devices that are both brighter and capable of operating at more different wavelengths than their predecessors. The high stability and absence of harmful ultraviolet and infrared radiation makes them an ideal choice for fluorescence and transmitted light microscopy. In common with our OptoLED, the Lite v…
Our flexible LaserBank system will launch up to five laser lines into up to five different single-mode fibres. This system can be configured with new lasers or, in most cases, with existing solid state lasers. Please contact us for details of your requirements. The flexible architecture allows lasers to be mounted for TIRF, FRAP, photolysis, confocal or widefield imaging. It provides analogue intensity control and digital swit…
Adjustable field mask for region selection For many years we have offered a movable variable rectangular field stop. This was initially designed to mask a region of interest within the field of view of a microscope in order to make localised intensity measurements with a photomultiplier. Subsequent evolutions of the device have formed an integral part of our OptoSplit image splitters to mask a region to be projected to both ha…
LumiScope for the detection of bioluminescence from aequorin and other luminescence probes.
The PatchPro systems are fully integrated patch clamping solutions that work in conjunction with fixed stage nosepiece focussing scopes from Olympus, Zeiss, Nikon and Leica. They allow the user to control manipulators, microscope platforms, microscope focus and temperature control all from one neat, simple user console. With the versatility to freely combine numerous individual devices, the PatchPro systems will be perfect for…
Crucial for every experimental setup is a stable mounting system. The Scientifica range of slice platforms, top plates and microscope stages has been developed for researchers using upright or inverted microscopes who would like to move outside the field of view of the objective. Various configurations can achieve this in different ways, either by translating the entire microscope between fixed apparatus, or where laser inputs…
The SliceMate is a temperature controlled submerged recording chamber for biological samples; neatly housed in one compact unit. It utilizes cutting edge technology to give outstanding temperature control in a compact, easy and convenient package which replaces the clumsy, slow reacting and problematic water bath designs. A peltier element allows you to heat or cool the solution whilst a data file of the actual temperature is…
The LBM-7 was designed and developed in conjunction with scientists to be stable, have low drift and be easy to use. It bridges the gap between coarse manipulators and micromanipulators. Affectionately known as the Little Blue Manipulator, this device can be easily configured from left to right-handed. With seven axes of movement, four linear and three rotational, combined with micron resolution, the LBM-7 was designed to serv…
Perfusion System for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 20 millisecond accuracyValveGuard™ technology detects bad valvesPrevent damage to your ValveLink and easily observe problem valves.Run experiments automatically - even unattendedMicroprocessor-based for accuracy and flexibilityBec…
* Combination inline heater plus multi-channel focal drug deliveryMaintain bath temperature and rapid drug wash-out with a high-flow bath line while quickly switching 8 preheated solutions through the Perfusion Pencil.® Steady 37°C at 5 ml/minute flow rates through both the bath line and tip. * Advanced auto-tuning temperature lockFuzzy logic PID software maintains chamber or reagent temperature to within 1°C of setpoint or be…
For programmable dispensing, microinjection, perfusion or spritzing of reproducible microliter volumes. Pulse a valve quickly for microliter delivery, or leave it on for constant perfusion. The short delivery path saves expensive reagents.• Deliver microliter volumes starting with as little as 100 microliters of precious drugsSwitch between eight solutions in milliseconds from a single tip• Minimize cross-contamination with Ba…
Bubbles in perfusion systems are caused by solution temperature changes. As solutions warm, they cannot hold as much gas, so they off-gas. This forms bubbles in perfusion tubing. It is especially true in inline heaters where the temperature rises dramatically. The best cure for bubbles is to pre-warm your solutions. AutoMate Scientific introduces the BubbleStop™ Syringe Heater with integrated temperature sensor and feedback. S…
Program your AutoMate Scientific ValveBank® valve and TTL on-off sequences with a Windows 98, 2000, or XP computer using 'click-and-drag' timebars. Save and load unlimited programs to disk, print-out program listings, then download your programs into the ValveBank's memory in one simple step.Features: *Supports up to 16 channels *Open multiple experiment windows *List programs to screen or printer *Supports all ValveBank…
12VDC solenoid valve controller for real-time or pre-programmed liquid switching in perfusion, physiology, biophysics, electrochemistry, or general liquid-handling research applicationsIncrease reproducibility with 10 millisecond accuracyStand-alone design - no computer necessaryRun experiments automatically - even unattendedMicroprocessor-based for accuracy and flexibilityBecause they lack a microprocessor, competing valve co…
0-10 psi precision pressure regulator, gauge and bubblers for oxygenation or gas saturation of perfusion reservoirs or syringes.Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to a tank/bottle of gas (30 to 100 psi).Elegant design allows individual control of each gas line.
Manifold and bubblers for oxygenation or gas saturation of perfusion liquids in reservoirs or syringes.Can be added to any new or existing perfusion rig - from AutoMate Scientific, any third-party manufacturer, even homemade.Connect to a tank/bottle of regulated gas (10 psi max).Elegant design allows individual control of each gas line.
An 8-into-1 multi-barrel manifold with male luer-lock fitting + removable tip available in 100, 250, or 360 micron internal diameter.Applications: *Single-cell and patch superfusion spritzing *Rapid (several millisecond) solution switching *Micro-liter dead volume8 micro-bore internal tubes come ready to connect to 1/16" i.d. tubing.Device is designed to mount in a micromanipulator.Materials: *Polypropylene, polyimide (ny…
Brownlee's rugged yet easy-to-use amplifiers have four channels of a high gain/low noise amplification, lowpass filter and output offset control. A control knob adjusts amplifier parameters, and an alphanumeric LED readout displays values. There is a memory function for each channel. Input voltage noise is only 1.5µV rms.The Brownlee Precision Model 410 is a four-channel general purpose laboratory amplifier (one channel shown)…
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![Perfusion Pencil® + Removable Tip [8 chan. manifold] - AutoMate Scientific Inc. - Life Sciences](https://cdn.sanity.io/images/f5b6mtfn/selectscience-prod/c2ea125d59a09e55ccb3185d96b9db552bf0fd0d-250x132.jpg?w=3840&q=75&fit=clip&auto=format)
