Process chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.
The FRX400 includes all the functionality of FRX300 but also has the full range of Syrris reactors, 4 Pumps, 2 Hotplates, 2 Reagent Modules and the Cooling Insert. This enables up to 4 inputs into a multi step reaction or 3 inputs and an immiscible aqueous work-up stream, reaction steps at different temperatures, cooling to -20°C and injection of small quantities of up to 4 reagents via sample loops. The FLLEX (Flow Liquid Liq…
The Atlas Syringe Pump is a versatile volumetric dosing system that consists of two syringes and can be configured into 2 refilling flows or 1 continuous flow. It can operate in isolation by use of the intuitive twist and click knob and display or can be controlled by the Atlas Base. A choice of dosing modes allows simple additions or intelligent active control of parameters including pH and temperature.
The Orbit from Syrris is a high performance, low cost parallel synthesis module for research and development chemistry. It fits conveniently on an Atlas hot plate, Atlas hot/cold plate or regular hotplate. 6 or 12 reaction tubes can be magnetically stirred in an inert atmosphere and be heated to 280°C with reflux or cooled to -40°C.
The Remote Mount allows a vessel assembly to be located away from the Atlas Base. The Remote Mount can attach to standard lab scaffolding and is connected to the Atlas base using an umbilical. When the Jacketed Vessel Clamp is used with the Remote Mount, it is compatible with vessels of up to 5 litres.
The Atlas Hot and Cold Plate is an easy and accurate way of heating and cooling reactions in flasks or vials. Designed to fit on the Atlas Base, the Hot and Cold Plate connects to a recirculating heater/cooler to provide temperature control from -40°C to +160°C. When a controllable circulator is connected to the Atlas Base, the Hot and Cold Plate or reaction can be accurately controlled to the temperature set on the Atlas Base…
Atlas Lithium automates reactions in round bottomed flasks or vials. The Hotplate and Stacking Dry Bath can heat round bottom flasks from 50ml to 1 litre (to 280°C) giving excellent thermal transfer to the reaction yet the exterior surface remains cool to the touch. The Atlas Clamp holds a range of different vessel sizes securely and automatically aligns flasks to the dry bath.
The Atlas Syringe Pump is a versatile volumetric dosing system that consists of two syringes and can be configured into 2 refilling flows or 1 continuous flow. It can operate in isolation by use of the intuitive twist and click knob and display or can be controlled by the Atlas Base. A choice of dosing modes allows simple additions or intelligent active control of parameters including pH and temperature.
Based on an Atlas Potassium, the Atlas Gravimetric Dosing system allows a defined mass of reagent to be pumped from a balance to the reactor by a controlled peristaltic pump. The mass flow rate can be defined, monitored and adjusted by using the Atlas Software.
Based on an Atlas Potassium, the Atlas Reaction Monitoring system includes additional temperature nodes and RTD probes to monitor the jacket temperature. The Reaction Monitoring system can use a combination of reaction temperature and jacket temperature to accurately monitor both exothermic and endothermic reaction processes either using the Atlas software or through the Atlas base.
AutoPlant / MultiPlant: Solutions for Process R&D, Polymer Synthesis and Preparative Synthesis The Chemspeed MultiPlant and AutoPlant workstations offer targeted solutions for Process R&D, Polymer Synthesis and Preparative Synthesis. The leading edge MiniPlant technology allows scientists to truly mimic the final industrial production process and provides all the required flexibility to optimize integrated reaction sequences,…
Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…
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Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH.Model Properties: Coat Color: Black MHC Haplotype: H2b Ideal For: general multipurpose model, diet-induced obesity, transgenic/knoc…
FlowSyn - Making Flow Chemistry Simple FlowSyn is a fully integrated continuous flow reactor with everything you need to start doing flow chemistry including reaction optimization, synthesis and scale up. To provide maximum flexibility, a wide range of mixer and reactor options are available as well as additional modules for performing multiple experiments, or sub-ambient chemistry. • Ability to perform continuous flow chemist…
USP Apparatus 4 Product Details:• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres • Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC • Evolution of t…
