UHPLC and HPLC Products & Reviews

The 1290 Infinity III Multisampler is a multipurpose autosampler that handles vials and microplates. Injecting at pressures up to 1300 bar, the Multisampler is a compact module with a capacity of up to 6,144 samples, all within the footprint of an Agilent LC stack.

Increase resolution where you need it with the 1290 Infinity III 2D-LC System, which offers comprehensive two-dimensional liquid chromatography (2D-LC), (multiple) heart-cutting 2D-LC analysis, and high-resolution sampling. This system allows you to use 2D-HPLC for making buffer separations compatible to MS detection, while easy-to-use software enables fast method setup and refined data analysis.

InfinityLab Quick Connect fittings are the only truly "finger-tight," reusable fitting for UHPLC, stable to 1300 bar. There are no tools needed… just use your fingers to close the lever for a perfect connection every time.

In order to more easily isolate and identify proteins in human serum, the Agilent Human 14 Multiple Affinity Removal Column is designed to chromatographically remove fourteen interfering high-abundant proteins from human plasma samples.

The 1260 Infinity II Prime LC is a versatile HPLC offering the highest functionality and operational convenience for analytical HPLC and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min. This versatile HPLC system is a perfect front end for your MS system. 

Agilent AdvanceBio SEC Protein Standards are uniquely designed for AdvanceBio SEC columns. The standards are manufactured from a select group of proteins and peptides optimized to deliver accurate, precise quantitation for mAb aggregation and protein analysis. 

Agilent Human Milk Oligosaccharide (formerly ProZyme) standards are highly purified standards for qualitative methods.

Agilent Poroshell columns are ideal for fast separations of proteins and peptides because the unique particle allows for fast flow rates to be used while maintaining sharp, efficient peaks. 

The 1260 Infinity II Preparative Binary Pump is an affordable high-pressure gradient pump for LC purification. The pump offers a dynamic flow rate range from 1 to 50 mL/min at up to 420 bar, allowing workflows on columns from 9.4 to 30 mm inner diameter.

The 1260 Infinity III RID is an HPLC refractive index detector (RID) detector that provides excellent performance for entry-level UHPLC and HPLC differential refractometer (DRI) experiments.

The 1260 Infinity III Diode Array Detector HS, with a fixed slit design, is based on the Agilent Max-Light Cartridge Cell with optofluidic waveguides, which improve light transmission to near 100% efficiency without sacrificing resolution caused by cell dispersion effects.

The 1260 Infinity III Fluorescence Detector offers time-programmable excitation and emission wavelength switching. The proven optical and electronic design provides the highest sensitivity for the analysis of trace-level components. This detector can be used with any Agilent InfinityLab LC Series system or other LC instrument.

The 1260 Infinity III Fluorescence Detector Spectra is a sensitive HPLC fluorescence detector that simultaneously provides quantitative data and fluorescence spectra from a single run, enabling rapid method optimization for HPLC FLD Detector Spectra experiments.

The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.

An ideal solution for trace level PFAS analysis with LC/MS/MS

The 1290 Infinity II Bio Flexible Pump is a UHPLC pump consisting of biocompatible material, designed for use in biopharma and other applications utilizing high-salt and extreme-pH conditions. It offers gradient formation from up to four solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.

InfinityLab solvent glass reservoirs are designed to provide high levels of performance for your LC applications.

The new InfinityLab lamps contain RFID technology for more convenience and ease of use. Agilent lamps are manufactured in an ISO 9001 certified environment and are fully traceable throughout every step of the production process. Each lamp is tested to ensure it meets Agilent performance specifications.

Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns provide good peak shape over a wide pH range (2–9) for additional method development flexibility with one family of columns. Eclipse XDB columns can be used for method development at low pH (2–3) and the same column can be used for method development in the mid pH (6–8) region.

Poroshell 120 columns provide rugged, high resolution separations within the pressure range of any mainstream LC system, making the benefits of sub-2 µm performance available with all existing LCs.Poroshell columns can achieve high resolution and high speed separations on current instruments, and higher resolution and speeds on new high-pressure LC and LC/MS systems. Stable to 600 bar, Poroshell 120 are great for fast UHPLC an…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications.The Ultra Aqueous C18 HPLC column provides reproducible retention times and can be used with highly aqueous mobile phases, which may eliminate the need for sample…

Properties: Increased retention for dipolar, unsaturated, or conjugated solutes. Enhanced selectivity when used with methanolic mobile phase. Ideal for increasing sensitivity and selectivity in LC-MS analyses particle size: 3 μm or 5 μm, spherical pore size: 100 Å carbon load: 15% endcap: fully endcapped pH range: 2.5 to 8 temperature limit: 80 °C USP phase: L11 phase category: phenyl ligand type: unique Biphenyl

Developed specifically for using LC coupled with GC-FID to accurately determine hydrocarbons found in mineral oils, which can migrate from packaging into food. • 9-component mix contains non-interfering internal standards as well as both mineral oil saturated hydrocarbon (MOSH) and mineral oil aromatic hydrocarbon (MOAH) markers to correctly cut fractions. • Certified reference material (CRM) manufactured and QC-tested in Re…

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

A Restek® LC guard cartridge in an EXP® direct connect holder is the ultimate in column protection.