UHPLC and HPLC Products & Reviews

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High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Ascentis® Express Biphenyl, 2.7 μm, HPLC Columns

Sigma-Aldrich Supelco

The Ascentis Express biphenyl phase chemistry offers alternative selectivity for pharmaceutical analytes and drug metabolites that are not well retained or difficult to resolve on traditional alkyl (C18) and phenyl bonded phases. Ascentis Express HPLC columns, through the use of Fused-Core® particle technology, can provide you with both the high speed and high efficiencies of sub-2 ?m particles while maintaining lower backp…

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Lux AMP Chiral Columns

Phenomenex Inc

Chiral analysis of amphetamine and substituted amphetamines Lux 3 µm AMP is a unique LC media with pH stability from 1-11.5 that was specifically developed for the chiral analysis of amphetamine and substituted amphetamines, including methamphetamine.

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Kinetex C8

Phenomenex Inc

Moderate hydrophobic and steric selectivity is offered, bringing ultra-high performance to USP L7 and other octyl silane methods.

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Thermo Scientific™ MAbPac™

Thermo Fisher Scientific

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over.

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SecurityCAP LC Solvent Safety Products

Phenomenex Inc

The SecurityCAP™ mobile phase and solvent waste safety caps prevent dangerous vapors and gases from leaving HPLC/ UHPLC solvent reservoirs. Over time, these chemicals can have a negative impact on the health of all employees and visitors in the lab. When lab safety and dependable results are a priority, you need SecurityCAPs.

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Luna Omega PS C18

Phenomenex Inc

Unique, 100 % aqueous stable mixed-mode phase that provides both polar and non-polar retention. The surface contains a positive charged ligand which aids in the retention of acidic compounds through ionic interactions, while the C18 ligand promotes general reversed phase retention. The positively charged surface also improves basic compound peaks shape through ionic repulsion. Available in: 1.6µm, 3µm, and 5µm

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Kinetex PAH

Phenomenex Inc

Kinetex PAH is the first polymerically bonded C18 core-shell column developed specifically for the analysis of PAHs from a wide variety of matrices. It can be used on both HPLC and UHPLC instrumentation and will easily shorten method run times, while improving overall resolution and sensitivity. To ensure a high standard of quality for the analysis of PAHs, Kinetex PAH is QC tested for the EPA 610 set of PAHs from water.

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Adept HPLC System 4S for Cannabis Analysis

Cecil Instruments Limited

Despite being a drug of abuse in many countries, many societies are currently experiencing an increasingly rapid acceptance of cannabis (marijuana) products for medicinal and recreational usage.  Additionally, low cannabis content and high hemp fibre products are grown in numerous countries. In addition to cannabinoid analysis of clinical samples, there is a need to determine the provenance, identification, purity and quant…

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AZURA® GPC Cleanup System

KNAUER Wissenschaftliche Geräte GmbH

Do not waste time and labor with manual sample preparation. The AZURA GPC Cleanup system automates work-intensive and time-consuming cleanup tasks based on gel permeation chromatography (GPC). Further, reproducibility and quality of the cleanup are improved. After sample loading, the dedicated system fully automatically processes up to 15 samples while requiring minimal bench space. Based on the versatile AZURA device platform…

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  • Best New Separations Product of the Year

50 cm µPAC™ column

PharmaFluidics

With an internal volume of 3µL, this 50 cm long RP-C18 µPAC™ column is perfectly suited to perform high throughput analyses with shorter gradi­ent solvent times (30, 60 and 90-minute gradients) and it can be used over a wide range of flow rates, between 100 and 2000 nL/min. µPAC™ column, 50 cm length, with pillar array backbone at interpillar distance of 2.5µm, C18.

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Flangeless Fittings

IDEX Health & Science

Flangeless Fittings eliminate the need to flange tubing. This removable and reusable system provides several benefits such as providing flangeless chromatography fittings for observing mixtures and solvents. Flangeless Fittings are easy to use. Just slip the nut and ferrule over the tubing and finger tighten the assembly into your receiving port. Our Flangeless Fitting require minimal downtime because component replacement is…

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Super Flangeless™ Fittings

IDEX Health & Science

Our Super Flangeless Fittings provide the highest pressure holding capability in a flat-bottom fitting system that we offer. Our unique design eliminates loosening of fittings due to tubing twist and holds tight even through vibration. Our high pressure fittings are excellent for tubing assemblies and those times when connections need to be broken frequently.

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Ultra High Pressure Valves

IDEX Health & Science

Our high pressure actuated valves are designed to be added to your existing instrument or to work optimally with stand-alone lab configurations. Our high pressure valves offer switching, injection, and selection valve functionality ideal for UHPLC applications. These valves have a pressure rating of up to 15000 psi (1035 bar).

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Thermo Scientific™ Vanquish™ Charged Aerosol Detector F

Thermo Fisher Scientific

Utilize the increased separation speed and resolution of the Thermo Scientific™ Vanquish™ UHPLC system to detect and quantify virtually any substance using the near-universal detection capabilities of Vanquish Charged Aerosol Detectors. Ideal for everyday analyses, the Thermo Scientific™ Vanquish™ Charged Aerosol Detector F offers enhanced linear dynamic range and accurate, consistent response. This detector can measure low-le…

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Thermo Scientific™ Vanquish™ Duo UHPLC System for Inverse Gradient LC

Thermo Fisher Scientific

Improve your productivity and sample knowledge for a faster return on investment with the Thermo Scientific™ Vanquish™ Duo UHPLC systems. Vanquish Duo UHPLC systems use a separate second flow path in one integrated system. With the Thermo Scientific™ Vanquish™ Duo UHPLC system for Inverse Gradient, improve your ability to detect and quantify all compounds in your sample with universal Charged Aerosol Detection using an Inverse…

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