Antigens Biomarkers Products & Reviews

Biomarker Detection System

Biomarker Measurement Detection

Protein Biomarker Testing and Custom Assay Development Services

pTau181 Biomarker Assay

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament majorly expressed in astrocytic glial cells in the central nervous system. Astrocytes play a variety of key roles in supporting, guiding, nurturing, and signaling neuronal architecture and activity. Monomeric GFAP is about 55kD. It is capable of forming both homodimers and heterodimers; GFAP can polymerize with other type III proteins or with neurofila…

The Simoa Human Neurology 2-Plex assay (N2PB) measures two important neurology biomarkers in both cerebrospinal fluid (CSF) and blood. The two targets are neurofilament light (Nf-L) and glial fibrillary acidic protein (GFAP™), which have been studied as indicators of traumatic brain injury (TBI) severity. N2PB has been developed as a 2-Plex version of the Neurology 4-Plex B assay (N4PB). *Banyan GFAP™ is a registered tradem…

The Quanterix Simoa® ALZpath p-Tau 217 Assay provides an ultrasensitive, reliable solution for detecting phosphorylated Tau 217 (p-Tau 217) in blood. This critical biomarker is essential for Alzheimer’s research, offering insights into disease progression and helping differentiate Alzheimer’s from other forms of dementia.

Sino Biological has developed a series of ADC target protein products, including well-established targets such as HER-2, TROP-2, Nectin-4, EGFR, CD19, and BCMA, as well as emerging targets like EphA3, GFRA1, CLEC7A.

Sino Biological has developed a panel of recombinant Fc receptor products covering diverse isoforms and their mutants; these products can be utilized in various applications such as antibody screening, bioactivity assays during the CMC stage, consistency evaluation, and safety validation.

Selected cancer related antigens translated into 15 amino acid peptides printed in duplicate

Flavivirus-specific selected antigens translated into 15 amino acid peptides printed in duplicate

Whole Zika virus proteome of two different strains as overlapping linear peptides

3,760 linear B-cell epitopes of 196 different pathogens

Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S1) is a recombinant antigen which contains the Spike protein amino acids 1-674. Spike S1 protein is manufactured in HEK293 mammalian cells, ensuring the most authentic post-translational modifications.

Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike S2 protein, amino acids 685-1211. Spike S2 is manufactured in mammalian HEK293 cells to ensure the most authentic post-translational modifications.

The Native Antigen Company offers a selection of complementary easy-to-use antibody conjugation formats, with a wide range of labels suitable for use in most applications. On request we can also undertake custom conjugation of proteins and antibodies.

With decades of experience in the field of native antigen and recombinant protein production, and assay development, The Native Antigen Company is able to undertake a wide range of custom projects on your behalf.  

SARS-CoV-2 Nucleoprotein is a recombinant antigen manufactured in E. coli cells to high purity for use in vaccine research and immunoassay development. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.

SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike protein amino acids 685-1211 of subunit 2. Spike S2 protein is manufactured to high yield and purity using the Native Antigens baculovirus-insect cell platform. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.

SARS-CoV-2 Spike-E-M Mosaic protein is a recombinant antigen manufactured in E. coli with greater than 95% purity, and containing the Spike (S), Envelope (E) and Membrane (M) immunodominant regions. SARS-CoV-2, previously known as the 2019 Novel Coronavirus (2019-nCoV), causes the pandemic COVID-19 disease.

Human Coronavirus 229E Nucleoprotein is a recombinant protein containing 359 amino acids derived from the nucleocapsid sequence, with a C-terminal 6xHis tag. It is manufactured in E. coli with greater than 95% purity.

Human Coronavirus NL63 Nucleoprotein is a recombinant protein containing the nucleocapsid C-terminal region (130 amino acids), cloned and expressed in E. coli, and purified by affinity chromatography (nickel column) with greater than 95% purity.

The xMAP® SARS-CoV-2 Multi-Antigen IgG Assay is a serological, multiplexed microsphere-based assay to measure the presence of IgG antibodies directed against the nucleocapsid protein (N), Receptor-Binding Domain (RBD) of the spike protein, and the S1 subunit of the spike protein (S1) of SARS-CoV-2 in human serum or plasma. The xMAP SARS-CoV-2 Multi-Antigen IgG Assay features: Broad Coverage: Detects IgG antibodies aga…