Immunology Products & Reviews

Opal 6-Plex Detection Kits - for Whole Slide Imaging (formerly Opal Polaris 7 Color IHC Detection Kits)

Tumors characterized as "hot" exhibit signs of inflammation, high T cell infiltration, and expression of PD-L1. These inflamed tumors typically respond well to checkpoint inhibitor immunotherapy. PhenoCode Signature Immuno-Contexture panel (CD8, CD68, PD-L1, FoxP3, PanCK) enables profiling of the tumor microenvironment for CD8+ T lymphocytes and PD-L1 expression. Map additional phenotypes by adding a 6th marker to the panel fr…

The composition of immune cells within the tumor microenvironment, such as T cells, B cells, and macrophages, varies between tumors and is strongly associated with outcomes to combination therapies. PhenoCode Signature Immune Profile panel enables profiling of the tumor microenvironment using 4 key immune cell markers (CD8, CD68, CD3e, CD20) and a tumor marker (PanCK). Map additional phenotypes by adding a 6th marker to the pa…

The ability to determine whether tumor cells are proliferating and T cells are activated could provide important information about the anti-tumor response and be an indicator of prognosis. PhenoCode Signature Activated TIL Status panel (CD8, CD3e, Ki67, Granzyme B, PanCK) enables determination of Ki67 positivity in addition to profiling of the tumor microenvironment for CD8+ T lymphocytes that are activated. Map additional phe…

Tumor associated macrophages (TAMs) play a key role in regulating the inflammatory or immunosuppressive state of the tumor microenvironemnt (TME). Distinguish between M1 (pro-inflammatory) and M2 (anti-inflammatory) TAMs using the PhenoCode™ Signature M1/M2 Polarization panel (CD8, CD68, CD163, PD-1, PD-L1) to evaluate polarization profiles in the TME. Map additional phenotypes by adding a 6th marker to the panel from the anti…

As the major population of immune cells within the tumor microenvironment (TME), T cells are a driver of anti-tumor immunity. T cell exhaustion and the presence of immunosuppressive cells can contribute to an immunosuppressive TME. PhenoCode™ Signature T Cell Status Panel (CD8, CD4, CD20, FoxP3, PD-1) allows for identification of distinct T Cell subsets and effector functionality status. Map additional phenotypes by adding a 6…

Orion Biomarkers  are tailored to enable spatial biomarker analysis with maximum flexibility. Choose from a range of labeled antibodies to generate Orion spatial biology data for multiplexed tissue imaging or create new reagents with easy-to-use conjugation kits.

Determination of total anti-infliximab antibodies Infliximab is a recombinant protein used to treat inflammatory bowel disease (IBD). The protein can induce humoral immune responses and lead to anti-drug antibody formation, a major cause of loss of drug response. IDKmonitor Infliximab Total Anti-drug ELISA kit is a ‘drug tolerant’ assay that enables the detection of anti-drug antibodies in the presence of circulating drug.

Determination of total anti-adalimumab antibodies Adalimumab is a recombinant protein used to treat inflammatory bowel disease (IBD). This protein can induce humoral immune responses and lead to anti-drug antibody formation, a major cause of loss of drug response. The IDKmonitor Adalimumab Total Anti-drug ELISA kit is a ‘drug tolerant’ assay that enables the detection of anti-drug antibodies in the presence of circulating dru…

Advanced centrifugal microplate washer and dispenser bringing high throughput into cellular assays.

The award-winning DxI 9000 Analyzer sets a new standard for today’s busy labs. With meaningful innovations that amplify your impact, liberate you from the laborious, and power your performance across your health system, this high-throughput immunoassay analyzer takes diagnostics to the next level.

X-tremeGENE siRNA Transfection Reagent efficiently delivers short interfering RNA (siRNA) into many commonly used cell types including HeLa, NIH 3T3, HEK-293, CHO-K1, and COS-7, and several hard-to-transfect cell lines such as HT29, a human adenocarcinoma cell line. When used for cotransfection-based gene knockdown, X-tremeGENE siRNA Transfection Reagent enables significant protein expression and effective knockdown levels due…

Use G-418 antibiotic to select and maintain eukaryotic cells that are stably transfected with the genes for neomycin resistance. High purity: Use less antibiotic and produce greater selection pressure while minimizing toxicity from contaminants. Convenient sterile-filtered liquid format: Reduce time, effort, and potential errors by using a prepared sterile-filtered solution instead of making stock solutions from powder.…

Culicoides Extract

Aldosterone LIA

Sample Type:Serum; Sample Size:50 µl; Size:96 Wells (LIA); ange:0.25 - 50 ng/ml; Sensitivity:0.1 ng/ml; Incubation Time:30 minutes

Estrone LIA

T4 (Thyroxine) (free) LIA

Testosterone (Free) LIA

Progesterone LIA

PSA (Prostate-Specific Antigen) (Total) LIA

Testosterone (Saliva) LIA

TSH (Thyroid Stimulating Hormone) LIA

Anti-Onconeural Antigens

Alport Syndrome Staining Kit