Enzymes Products & Reviews

AMPK activator

Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3 and STAT5a/b

Epigenetic modifier; Inhibits SIRT2 histone deacetylase

PI3K/AKT pathway inhibitor; Inhibits AKT1, AKT2, AKT3

PI3K/AKT pathway inhibitor; Inhibits AKT

Retinoid pathway activator; Activates retinioc acid receptor (RAR) alpha

Epigenetic modifier; Inhibits histone acetyltransferase (HAT)

MEK/ERK pathway inhibitor; Inhibits B-RAF, B-RAFV600E and C-RAF-1

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

mTOR pathway inhibitor; Inhibits mTOR

Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

WNT pathway activator; Inhibits GSK3

WNT pathway activator; Inhibits GSK3

p38 MAPK inhibitor

Epigenetic modifier; Inhibits G9a histone methyltransferase

NF-?B Pathway Inhibitor; Stabilizes I?B

Epigenetic modifier; Inhibits histone deacetylase (HDAC) 6

Src family kinases inhibitor; Inhibits Src, LCK, Yes, Cdc2, EGFR, VEGFR, v-Abl, and FAK

Epigenetic modifier; Inhibits histone methyltransferases SU(VAR)3-9

WNT pathway activator; Inhibits GSK3

Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein

p53 Inhibitor

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK

MEK/ERK pathway inhibitor; Inhibits B­RAF V600E

Notch pathway inhibitor; Inhibits ?-secretase