Enzymes Products & Reviews

Cyclin/CDK pathway inhibitor; Inhibits CDK1 and CDK2

Tryosine kinase inhibitor and epigenetic modifier; Inhibits PDGF, FGF, EGF, TGFß, SIRT1, and SIRT5

JAK/STAT pathway inhibitor; Inhibits JAK2

RHO/ROCK pathway inhibitor; Inhibits ROCK

mTOR pathway inhibitor; Inhibits mTORC1 and mTORC2 complexes

Epigenetic modifier; Inhibits lysine-specific demethylase 1 (LSD1)

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1 and HDAC6

WNT pathway activator; Inhibits GSK3ß

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1

Tyrosine kinase inhibitor; Inhibits VEGFR1, KDR, FLT-4, EGFR, FGFR, ABL, RET, and SRC

JAK/STAT pathway inhibitor; Inhibits JAK3

JAK/STAT pathway inhibitor; Inhibits JAK3

PI3K/AKT pathway inhibitor; Inhibits PI3K and PLKs

WNT pathway inhibitor; Inhibits TNKS1 and TNKS2

Epigenetic modifier; Inhibits DNA methyltransferases (DNMT)

Inhibitor of bone resorption; Inhibits farnesyl diphosphate (FPP) synthase

Non-muscle myosin II (NM II) ATPase inhibitor

Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; I?B activator

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

Inhibits glycogen synthase kinase 3ß (GSK3ß)

Prostanoid pathway activator; Inhibits 15-hydroxy PGDH

Epigenetic modifier; Inhibits histone EZH2 lysine methyltransferase

Activates nuclear factor erythroid 2-related factor 2 (Nrf2) protein

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits ALK5, ALK4, and ALK7