Thymidine Phosphorylase, recombinant from Escherichia coli
Merck KGaA, Darmstadt, Germanyrecombinant, expressed in E. coli, buffered aqueous solution, ?500 units/mL
recombinant, expressed in E. coli, buffered aqueous solution, ?500 units/mL
thymidylate synthase inhibitor
MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2
Activin/Nodal/TGFß pathway inhibitor; Inhibits ALK5
Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK5
Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
RHO/ROCK pathway inhibitor; Inhibits ROCK2
cAMP pathway activator; Inhibits type 4 cyclic nucleotide phosphodiesterases (PDE4)
WNT pathway activator; Inhibits GSK3a and GSK3ß
Activin/BMP/TGF-ß pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
Epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)
Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2
Activin/NODAL/TGF-ß pathway inhibitor; Inhibits SMAD3
JNK pathway inhibitor; Inhibits JNK1, JNK2 and JNK3
JAK/STAT pathway inhibitor; Inhibits STAT5
Calcium signaling inhibitor; Inhibits calcium/calmodulin-dependent kinase kinases (CaMKKs)
MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
Tyrosine kinase inhibitor; Inhibits of KDR, PDGFR, KIT, RET, FLT-3, ABL and ALK